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Manforce 100 mg is a generic version of sildenafil, a phosphodiesterase-5 (PDE5) inhibitor, commonly used to treat erectile dysfunction (ED). While it shares a similar mechanism of action with other PDE5 inhibitors, there are several factors that differentiate it from other generic ED medications. These include composition, pricing, onset of action, and duration of effect. 1. Active Ingredient Manforce 100 mg contains sildenafil as its active ingredient, the same as Viagra, which is the original brand-name medication for ED. However, other generic ED medications might use different active ingredients, such as tadalafil (found in Cialis) or vardenafil (found in Levitra). These variations can lead to differences in how long the medication lasts and how quickly it starts to work. Sildenafil (Manforce 100 mg) typically takes around 30 minutes to an hour to begin working, and its effects last for about 4 to 6 hours. Tadalafil (Cialis) has a longer duration, lasting up to 36 hours, which is why it is sometimes referred to as the "weekend pill." Vardenafil (Levitra) works similarly to sildenafil but might be more potent for some individuals and also has a shorter time to onset. 2. Duration of Effect The duration of action is one of the key differences between Manforce 100 mg and other ED medications. Manforce 100 mg (sildenafil): The effects typically last for about 4-6 hours, which is suitable for men who prefer spontaneous sexual activity within that window. However, for some users, the shorter duration could mean more planning is required. Tadalafil (Cialis): Known for its "long-lasting" effect, Cialis can work for up to 36 hours, allowing for more flexibility and spontaneity.