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Tazzle, which contains tadalafil, can have specific risks depending on various health conditions. Here are some considerations: Cardiovascular Issues: If you have a history of heart problems, using Tazzle may increase the risk of cardiovascular events, especially if engaging in sexual activity. Low Blood Pressure: Tazzle can lower blood pressure, so if you have hypotension or are taking medications for high blood pressure, there could be a risk of further lowering your blood pressure. Liver or Kidney Disease: Impaired liver or kidney function can affect the metabolism of tadalafil, potentially increasing the risk of side effects. Retinitis Pigmentosa: Tazzle with this rare eye condition may have an increased risk of vision problems when using Tazzle. Blood Disorders: If you have conditions like sickle cell anemia, multiple myeloma, or leukemia, there may be an increased risk of complications. Allergic Reactions: If you have a known allergy to tadalafil or any other components of Tazzle, you should avoid its use. Always consult with a healthcare provider before starting any new medication, especially if you have existing health conditions or are taking other medications. They can provide personalized advice and assess your specific situation.