Forum > Topic Details


How Does Vilitra 20 Affect Liver Function?

How Does Vilitra 20 Affect Liver Function?

by Rony meran (Posts: 0) » about 3 days ago

Vilitra 20, containing the active ingredient Vardenafil, is primarily used for treating erectile dysfunction. Like any medication, it can have effects on the liver, which plays a crucial role in metabolizing drugs. Here’s an overview of how Vilitra 20 might affect liver function: Metabolism and Liver Function Liver Metabolism: CYP3A4 Enzyme: Vardenafil is primarily metabolized in the liver by the enzyme cytochrome P450 3A4 (CYP3A4). First-Pass Metabolism: When taken orally, Vardenafil undergoes significant first-pass metabolism in the liver, reducing its bioavailability. Impact on Liver Enzymes: Potential Elevation: In some cases, Vardenafil might cause mild elevations in liver enzymes (such as ALT and AST), which are indicators of liver function. Monitoring: Patients with pre-existing liver conditions or those taking other medications metabolized by CYP3A4 should have their liver function monitored. Effects on Individuals with Liver Conditions Mild to Moderate Liver Impairment: Dosage Adjustment: For individuals with mild to moderate liver impairment, a lower dose of Vardenafil is often recommended due to slower metabolism and increased drug exposure. Increased Risk: There is a potential for increased side effects and prolonged action of the drug. Severe Liver Impairment: Contraindications: Vilitra 20 is generally not recommended for individuals with severe liver impairment (Child-Pugh Class C) due to significantly altered drug metabolism and potential for adverse effects.

(0) Answer(s)